Peer-reviewed veterinary case report
Kobuvirus found in UK dogs and cats but rare in diarrhea cases
By Carmona-Vicente, N et al.·Published in Veterinary microbiology·2013·Department of Microbiology, Spain·View original on PubMed →
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Original publication title: Phylogeny and prevalence of kobuviruses in dogs and cats in the UK.
- Species:
- dog
Plain-English summary
A dog in the UK was found to have a rare virus called kobuvirus after experiencing diarrhea. Researchers discovered this virus is not common among dogs, as it was only identified in one case during a study on canine diarrhea. They also found that cats might be susceptible to this virus, as antibodies were detected in cat blood samples. Although the virus was present, it does not seem to pose a significant risk to pets or humans.
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Abstract
The kobuviruses represent an emerging genus in the Picornaviridae. Here we have used next generation sequencing and conventional approaches to identify the first canine kobuvirus (CaKoV) from outside the USA. Phylogenetic analysis suggests that a single lineage genotype of CaKoV now exists in Europe and the USA with 94% nucleotide similarity in the coding region. CaKoV was only identified in a single case from a case-control study of canine diarrhoea, suggesting this virus was not a frequent cause of disease in this population. Attempts to grow CaKoV in cell culture failed. Sequence analysis suggested CaKoV was distinct from human Aichi virus (AiV), and unlikely to pose a significant zoonotic risk. Serosurveys by ELISA, immunofluorescence and neutralisation tests, using AiV as antigen, suggested kobuvirus infection is prevalent in dogs. In addition, IgG antibody to AiV was also detected in cat sera, indicating for the first time that cats may also be susceptible to kobuvirus infection.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/23490561/