Peer-reviewed veterinary case report
Cat with swollen, peeling paw pads linked to FeLV and FIV infections
By Biezus, Giovana et al.·Published in Topics in companion animal medicine·2020·Department of Veterinary Medicine, Brazil·View original on PubMed →
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Original publication title: Plasma Cell Pododermatitis Associated With Feline Leukemia Virus (FeLV) and Concomitant Feline Immunodeficiency Virus (FIV) Infection in a Cat.
- Species:
- cat
Plain-English summary
A 2-year-old mixed-breed cat was brought in with swollen, painful paw pads, skin peeling, and redness. The vet found that the cat had both feline leukemia virus (FeLV) and feline immunodeficiency virus (FIV) infections, which contributed to a condition called plasma cell pododermatitis (a skin problem affecting the paws). After thorough testing, including blood work and biopsies, the diagnosis was confirmed. Treatment details weren't specified, but managing the underlying viral infections is crucial for recovery.
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Abstract
This report aims to describe one case of plasma cell pododermatitis associated with feline leukemia virus (FeLV) and concomitant feline immunodeficiency virus (FIV) infection in a cat. A 2-year-old, intact male, mixed-breed cat was presented with alopecia, skin peeling, and erythematous swelling in the left metacarpal paw pad. Swelling, softening, ulceration with secondary crusts, and erythematous to violaceous discoloration were observed in multiple metacarpal, metatarsal, and digital paw pads. Complete blood count and serum biochemistry were analyzed. FeLV antigenemia and FIV seropositivity were assessed by immunoassay (enzyme-linked immunosorbent assay). Nested-PCR was used to detect FIV and FeLV proviral DNA in blood cells. Histopathological examination and anti-FeLV and anti-FIV immunohistochemical were performed on paw pad biopsies. According to clinical and histopathological findings, a diagnosis of plasma cell pododermatitis was made. The cat was FIV and FeLV seropositive. The immunohistochemical of paw pad biopsies revealed FeLV positivity and FIV negativity. This study provides reference for further investigations about feline plasma cell pododermatitis and highlights retrovirus infection as a potential factor associated with this disease.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/32966900/