Peer-reviewed veterinary case report
Plasma concentrations of lidocaine in dogs following lidocaine patch application.
- Journal:
- Journal of the American Animal Hospital Association
- Year:
- 2007
- Authors:
- Ko, Jeff et al.
- Affiliation:
- Department of Veterinary Clinical Sciences · United States
- Species:
- dog
Abstract
Transdermal absorption of lidocaine was determined by measuring plasma lidocaine concentrations following skin application of 5% lidocaine patches. Two lidocaine patches were placed on the ventral abdominal midline of seven dogs for 72 hours. Lidocaine was detectable in plasma 12 hours after patch application, and it reached steady-state concentrations between 24 and 48 hours. Plasma lidocaine levels decreased dramatically at 60 hours post-application. Low plasma lidocaine concentrations remained for 6 hours after patch removal. No clinically significant side effects were noted.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/17823477/