Peer-reviewed veterinary case report
Plasma lipids, lipoprotein composition and profile during induction and treatment of hepatic lipidosis in cats and the metabolic effect of one daily meal in healthy cats.
- Journal:
- Journal of animal physiology and animal nutrition
- Year:
- 2004
- Authors:
- Blanchard, G et al.
- Affiliation:
- UP de Nutrition · France
- Species:
- cat
Plain-English summary
Obese cats that stop eating can develop a serious condition called feline hepatic lipidosis (FHL), which affects their liver. This study looked at the levels of fats and proteins in the blood of female cats at different stages of FHL and after they received treatment for 10 weeks. It found that FHL causes an increase in certain types of fats in the blood, indicating that the way the body processes these fats is not working properly. Additionally, cats that were fed just one meal a day had higher cholesterol levels compared to those that could eat whenever they wanted. The study highlights the importance of monitoring diet in cats, especially those that are overweight or not eating well.
Abstract
Anorexia in obese cats may result in feline hepatic lipidosis (FHL). This study was designed to determine plasma lipids and lipoprotein profiles in queens at different stages during experimental induction of FHL (lean, obese, FHL), and after 10 weeks of treatment. Results were compared with those obtained from lean queens of same age fed the same diet but at a maintenance level, once a day. Hepatic lipidosis led to an increase in plasma triacylglycerol (TG), very low density lipoprotein (VLDL) and low density lipoprotein (LDL), and an enrichment of LDL with TG and of high density lipoprotein (HDL) with cholesterol, suggesting that VLDL secretion is enhanced, VLDL and LDL catabolism is lowered, and lipoprotein exchanges are impaired in FHL. This study also showed that cholesterolaemia is increased in cats fed at a dietary rhythm of one meal per day compared to ad libitum feeding.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/15059230/