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Peer-reviewed veterinary case report

Plasma transferrin levels rise after nutrition treatment

By Nakajima, Mayumi et al.·Published in The Journal of veterinary medical science·2014·Department of Veterinary Internal Medicine, Japan·View original on PubMed

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Original publication title: Plasma transferrin concentration as a nutritional marker in malnourished dogs with nutritional treatment.

Species:
dog
Appetite & weightDogs

Plain-English summary

A group of malnourished dogs was evaluated for their nutritional status by measuring a protein called transferrin in their blood before and after they received nutritional treatment. After treatment, the dogs showed higher transferrin levels, which were linked to weight gain and better overall health. Dogs with transferrin levels above a certain point had a higher chance of surviving 60 days after starting treatment compared to those with lower levels. This suggests that measuring transferrin could be a helpful way to assess nutrition in dogs.

People also search for: dog malnutrition treatment · how to help a malnourished dog · dog weight gain after treatment

Abstract

Rapid turnover proteins, such as transferrin (Tf), are used as dynamic nutritional assessment proteins in human medicine. However, nutritional status in veterinary medicine is mostly assessed on the basis of classical static factors, such as body weight, body condition score and plasma albumin level. This study evaluated the clinical usefulness of Tf as a nutritional assessment marker by measuring plasma Tf concentrations in malnourished dogs before and after nutritional treatment. Posttreatment plasma Tf concentrations were significantly higher than the pretreatment concentrations, although the albumin concentration did not change significantly. The numbers of dogs that exhibited increases in plasma Tf concentrations were significantly related to weight gain. Furthermore, the survival rates at day 60 after treatment initiation were significantly higher in dogs with plasma Tf concentrations above the reference value (180 mg/dl) after the nutritional treatment than in those with a plasma Tf concentration<180 mg/dl. In conclusion, the plasma Tf concentration is related to nutritional condition and would be a candidate for a novel nutritional assessment marker in dogs.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/24366156/