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Peer-reviewed veterinary case report

Platelet-rich plasma application for the management of early-stage Canine Legg-calve-perthes disease: A clinical case report

Journal:
Open Veterinary Journal
Year:
2025
Authors:
Viktoras Sinkevičius et al.
Affiliation:
Šiaulių str. 7 · LY
Species:
dog

Abstract

Background: Legg-Calve-Perthes Disease (LCPD) is characterized by ischemic necrosis of the femoral head, primarily affecting small breed dogs. Case Description: An 11-month-old, female Toy Poodle presented with hindlimb lameness due to LCPD, previously treated unsuccessfully with NSAIDs. Platelet-Rich Plasma (PRP) was administered intra-articularly. Clinical evaluations included lameness scoring, range of motion (ROM), thigh girth measurements, and radiographic assessment. Conclusion: PRP administration resulted in significant clinical improvement, reduction in lameness, pain relief, cessation of bone lysis, and increased muscle mass by day 44 post-treatment. [Open Vet. J. 2025; 15(10.000): 5415-5419]

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Original publication: https://doi.org/10.5455/OVJ.2025.v15.i10.60