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Peer-reviewed veterinary case report

Platelet-rich plasma application for the management of early-stage Canine Legg-calvé-perthes disease: A clinical case report.

Journal:
Open veterinary journal
Year:
2025
Authors:
Sinkevičius, Viktoras et al.
Affiliation:
ius Veterinary Clinic
Species:
dog

Abstract

BACKGROUND: Legg-Calvé-Perthes disease (LCPD) is characterized by ischemic necrosis of the femoral head, primarily affecting small-breed dogs. CASE DESCRIPTION: An 11-month-old female toy poodle presented with hindlimb lameness due to LCPD. The dog was treated with intra-articular injection of platelet-rich plasma (PRP), and clinical improvement was evaluated using lameness scoring, range of motion, thigh girth measurements, and radiographic assessment. CONCLUSION: PRP administration resulted in significant clinical improvement, including reduction in lameness, minimal requirement of pain relief, cessation of bone lysis, and increased muscle mass by day 44 post-treatment.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/41246420/