Peer-reviewed veterinary case report
Platelet-rich plasma treatment for dogs with hip arthritis
By Alves, J C et al.·Published in BMC veterinary research·2021·Divisã·View original on PubMed →
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Original publication title: Platelet-rich plasma therapy in dogs with bilateral hip osteoarthritis.
- Species:
- dog
Plain-English summary
A group of 20 police dogs with hip osteoarthritis (OA) received injections of platelet-rich plasma to help reduce pain and improve movement. The dogs were evaluated over several months, and those treated with platelet-rich plasma showed better results compared to those who received a saline solution. The improvements in pain and function lasted longer for the dogs that received the platelet-rich plasma treatment. This suggests that this therapy could be beneficial for dogs suffering from hip OA.
People also search for: dog hip arthritis treatment · platelet-rich plasma for dogs · police dog joint pain relief
Abstract
BACKGROUND: Osteoarthritis (OA) is the most commonly diagnosed joint disease in companion animals, and hip OA is commonly diagnosed in the canine population. The use of platelet-rich plasma has gained increasing interest for the treatment of musculoskeletal conditions in companion animals. To evaluate the effect of the intra-articular administration of platelet-rich plasma in police working dogs with bilateral hip OA compared to a control group, twenty dogs were assigned to a control group (CG, n = 10) or treatment group (PG, n = 10), using the statistical analysis software. PG received two intra-articular administrations of platelet-rich plasma, 14 days apart, while CG received an intra-articular administration of saline, in the same moments. Response to treatment was determined with the Canine Brief Pain Inventory, Liverpool Osteoarthritis in Dogs, Canine Orthopedic Index, and Hudson Visual Analogue Scale, before treatment, + 8, + 15, + 30, + 60, + 90, + 120, 150, and + 180 days after initial treatment. Kaplan-Meier estimators were conducted and compared with the log-rank test. Cox proportional hazard regression analysis was performed to determine treatment survival, p < 0.05. RESULTS: The sample comprised 20 animals of both sexes (male n = 12, female n = 8), with a mean age of 8.4 ± 2.4 years and a bodyweight of 31.5 ± 5.7 kg. Joints were classified as moderate (13) and severe (7) according to the Orthopedic Foundation for Animals grading scheme. No differences were found between groups at the initial evaluation. Better results with the majority of scores were observed in the PG, in some cases lasting up to the last evaluation moment. Kaplan-Meier estimators showed that PG produced longer periods with better results in all scores compared to CG. Treatment was the covariate influencing all scores in the Cox regression analysis. OFA hip score also influenced two dimensions of the Canine Orthopedic Index. CONCLUSION: The intra-articular administration of platelet-rich plasma can improve pain and functional scores of police working dogs with bilateral hip OA, compared with a control group. Its effects lasted for significantly longer periods, and treatment was the main covariate affecting the improvements observed.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/34090433/