Peer-reviewed veterinary case report
Platelet α-granules contribute to organ-specific pathologies in a mouse model of severe malaria.
- Journal:
- Blood advances
- Year:
- 2020
- Authors:
- Darling, Thayer K et al.
- Affiliation:
- Department of Pathology
- Species:
- rodent
Abstract
Nbeal2 deficiency leads to significantly reduced lung and brain pathology and enhanced survival in a mouse model of malaria. Both antibody-dependent and antibody-independent platelet depletion in mice recapitulate the findings observed inmice.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/31891656/