Peer-reviewed veterinary case report
Plug-based microfluidics with defined surface chemistry to miniaturize and control aggregation of amyloidogenic peptides.
- Journal:
- Angewandte Chemie (International ed. in English)
- Year:
- 2009
- Authors:
- Meier, Matthias et al.
- Affiliation:
- Department of Chemistry · United States
- Species:
- rodent
Abstract
Small with control: For miniaturization of protein aggregation experiments the interfacial chemistry must be controlled to avoid protein aggregation caused by interfacial adsorption. Plug-based microfluidics with defined surface chemistry (see schematic picture) can then be used to perform hundreds of aggregation experiments with volume-limited samples, such as cerebrospinal fluid from mice.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/19152390/