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Peer-reviewed veterinary case report

Polioencephalomyelopathy in a mixed breed dog resembling Leigh's disease.

Journal:
The Canadian veterinary journal = La revue veterinaire canadienne
Year:
2015
Authors:
Chai, Orit et al.
Affiliation:
Veterinary Teaching Hospital
Species:
dog

Abstract

A 14-month-old mixed-breed dog was presented with acute onset of exercise intolerance that quickly progressed to quadriparesis. Gross and microscopic autopsy findings indicated a type of degenerative polioencephalomyelopathy resembling subacute necrotizing encephalomyelopathy in dogs or Leigh's disease in humans. This syndrome has previously been reported only in purebred dogs.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/25565716/