Peer-reviewed veterinary case report
Polycystic kidney disease and cyst infection treated in British
By Nivy, R et al.·Published in The Journal of small animal practice·2015·Department of Small Animal Internal Medicine·View original on PubMed →
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Original publication title: Polycystic kidney disease in four British shorthair cats with successful treatment of bacterial cyst infection.
- Species:
- cat
Plain-English summary
Four British shorthair cats were diagnosed with polycystic kidney disease, a genetic condition that leads to kidney cysts and reduced kidney function. One of the cats developed an infection in a renal cyst, which was successfully treated. This case highlights a rare complication of polycystic kidney disease in cats, similar to what can occur in humans. The treatment helped improve the cat's condition, demonstrating that even with this inherited disorder, effective management is possible.
People also search for: British shorthair cat kidney disease · cat kidney cyst infection treatment · polycystic kidney disease in cats symptoms
Abstract
Polycystic kidney disease is the most common inherited disorder in cats. Renal cysts progressively increase in size and number, resulting in a gradual decrease in kidney function. An autosomal dominant mutation in exon 29 of the polycystin-1 gene has been identified, mostly in Persian and Persian-related breeds. This case study describes polycystic kidney disease in four British shorthair cats, of which two had the same genetic mutation reported in Persian and Persian-related cats. This likely reflects introduction of this mutation into the British shorthair breeding line because of previous outcrossing with Persian cats. An infected renal cyst was diagnosed and successfully treated in one of the cats. This is a commonly reported complication in human polycystic kidney disease, and to the authors' knowledge has not previously been reported in cats with polycystic kidney disease.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/25677715/