Peer-reviewed veterinary case report
Polymorphism of the PE domain of PE/PE_PGRS sequences in clinical isolates of Mycobacterium bovis in Mexico.
- Journal:
- Veterinary microbiology
- Year:
- 2006
- Authors:
- Santillan-Flores, Marco Antonio et al.
- Affiliation:
- Instituto Nacional de Investigaciones Forestales
Abstract
Polymorphism of the PE domain of PE/PE_PGRS sequences was studied in Mycobacterium bovis isolates from different Mexican states. Samples were analyzed by spolygotyping and RFLP using IS6110 and a 235-bp fragment of the PE domain of PE/PE_PGRS as probes. With the PE probe, three different genotypes were observed, one being predominant in all states. These results confirm the high conservation of the PE domain and suggests a potential role for PE sequence as a stable genetic marker for bovine tuberculosis.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/16638629/