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Peer-reviewed veterinary case report

Dog with blood in urine diagnosed with eosinophilic bladder cystitis

By Ozaki, Kiyokazu et al.·Published in The Journal of veterinary medical science·2008·Department of Pathology, Japan·View original on PubMed

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Original publication title: Polypoid eosinophilic cystitis with pseudosarcomatous proliferative tissue in a dog.

Species:
dog

Plain-English summary

A dog was brought in for blood in its urine (hematuria), and the vet found two small growths in the bladder. These growths were made up of various types of cells, including some that are typically involved in inflammation. After examining the tissue, the vet diagnosed the dog with eosinophilic cystitis, which is a condition where the bladder tissue becomes inflamed and forms polyps. Fortunately, the growths showed low activity and were not aggressive, which is a positive sign for treatment and recovery.

People also search for: dog blood in urine · dog bladder polyp treatment · eosinophilic cystitis in dogs

Abstract

A dog presented with hematuria, and two small polypoid masses were detected in the urinary bladder. Histopathologically, the masses were located in the mucosal or submucosal layer. That tissue consisted of a random proliferation of spindle-shaped, round and pleomorphic cells with single or multiple large atypical nuclei and abundant cytoplasm, and eosinophil infiltration. These large cells were confirmed by immunohistochemical staining as fibroblasts, myofibroblasts and macrophages. Mitotic figure was rarely seen. These masses were diagnosed as eosinophilic polypoid cystitis with pseudosarcomatous proliferative tissue, since they consisted of a wide variety of cells and showed low growth activity.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/18388430/