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Peer-reviewed veterinary case report

Polysulfated Glycosaminoglycan as a Novel, Adjunctive Therapy for Pemphigus Foliaceus in Three Dogs.

Journal:
Journal of the American Animal Hospital Association
Year:
2019
Authors:
Simpson, Andrew et al.
Affiliation:
From the Department of Clinical Sciences · United States
Species:
dog

Abstract

Three dogs who were presented with cutaneous lesions and had histopathologic findings consistent with pemphigus foliaceus were treated with injectable polysulfated glycosaminoglycan as an adjunctive to systemic immune-modulatory therapy. These patients were not adequately controlled with oral glucocorticoids in conjunction with cyclosporine, azathioprine, and/or mycophenolate. Polysulfated glycosaminoglycan contributed to induction of remission and reduced glucocorticoid doses in all dogs.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/31525095/