Peer-reviewed veterinary case report
New treatment helps control pemphigus skin disease in dogs
By Simpson, Andrew et al.·Published in Journal of the American Animal Hospital Association·2019·From the Department of Clinical Sciences, United States·View original on PubMed →
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Original publication title: Polysulfated Glycosaminoglycan as a Novel, Adjunctive Therapy for Pemphigus Foliaceus in Three Dogs.
- Species:
- dog
Plain-English summary
Three dogs with skin lesions caused by a condition called pemphigus foliaceus (an autoimmune skin disease) were not responding well to their usual medications, which included oral steroids and other immune-suppressing drugs. Their veterinarians added an injectable treatment called polysulfated glycosaminoglycan to their care. This new treatment helped all three dogs achieve remission and allowed for lower doses of steroids.
People also search for: dog skin lesions treatment · pemphigus foliaceus in dogs · injectable treatment for dog skin problems
Abstract
Three dogs who were presented with cutaneous lesions and had histopathologic findings consistent with pemphigus foliaceus were treated with injectable polysulfated glycosaminoglycan as an adjunctive to systemic immune-modulatory therapy. These patients were not adequately controlled with oral glucocorticoids in conjunction with cyclosporine, azathioprine, and/or mycophenolate. Polysulfated glycosaminoglycan contributed to induction of remission and reduced glucocorticoid doses in all dogs.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/31525095/