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Peer-reviewed veterinary case report

Porcine models of cutaneous wound healing.

Journal:
ILAR journal
Year:
2015
Authors:
Seaton, Max et al.
Affiliation:
is a general surgery resident at the University of Maryland Medical Center in Baltimore · United States

Abstract

Cutaneous wound healing in the pig is frequently used as a model for human cutaneous wound healing. In this review, we examine the appropriateness of this model for studying normal and pathological wound healing, and describe models for chronic nonhealing wounds, diabetic wounds, burns, and hypertrophic scars. In addition, we focus on studies that have used pigs to evaluate wound-healing therapies, and discuss genetic engineering technology in the pig that may advance our knowledge of wound healing. We conclude that, although not perfect, the pig offers a versatile model that can be adjusted to mimic a wide range of clinical scenarios.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/25991704/