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Peer-reviewed veterinary case report

Sphinx cat with skin bumps and eye inflammation diagnosed with FIP

By Bauer, Bianca S et al.·Published in Veterinary ophthalmology·2013·Department of Small Animal Clinical Sciences, Canada·View original on PubMed

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Original publication title: Positive immunostaining for feline infectious peritonitis (FIP) in a Sphinx cat with cutaneous lesions and bilateral panuveitis.

Species:
cat

Plain-English summary

A 2-year-old spayed female Sphinx cat was brought to the vet with eye problems and skin bumps. The cat had bilateral panuveitis (inflammation in both eyes) and multiple skin lesions. After a biopsy, the vet found signs of feline infectious peritonitis (FIP), a serious viral disease that can be fatal. Although FIP is usually difficult to diagnose before death, the skin lesions helped confirm the diagnosis. Unfortunately, FIP is a severe condition, and treatment options are limited, so the prognosis is often poor.

People also search for: cat eye problems · Sphinx cat skin lesions · FIP treatment options · feline infectious peritonitis symptoms · cat panuveitis causes

Abstract

Feline infectious peritonitis (FIP) is a common, fatal, systemic disease of cats. This case report describes the antemortem diagnosis of FIP in a 2-year-old spayed female Sphinx cat that presented with a bilateral panuveitis and multiple papular cutaneous lesions. Histopathologically, the skin lesions were characterized by perivascular infiltrates of macrophages, neutrophils, with fewer plasma cells, mast cells, and small lymphocytes in the mid- to deep dermis. Immunohistochemistry for intracellular feline coronavirus (FeCoV) antigen demonstrated positive staining in dermal macrophages providing an antemortem diagnosis of a moderate, nodular to diffuse, pyogranulomatous perivascular dermatitis due to FIP infection. Obtaining an antemortem diagnosis of FIP can be a challenge and cutaneous lesions are rare in the disease. Recognition and biopsy of any cutaneous lesions in cats with panuveitis and suspected FIP can help establish an antemortem diagnosis of the disease.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/23607772/