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Peer-reviewed veterinary case report

Dog developed fatal colitis after antibiotic treatment

By Willard, M D et al.·Published in Journal of the American Veterinary Medical Association·1998·Department of Small Animal Medicine, United States·View original on PubMed

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Original publication title: Possible antibiotic-associated colitis in a dog.

Species:
dog

Plain-English summary

A Poodle with kidney disease developed severe diarrhea and other colonic issues after being given antibiotics. Tests showed a significant disruption in the normal bacteria in the dog's gut, which suggested that the antibiotics caused a serious condition called antibiotic-associated colitis. Unfortunately, despite medical efforts, the condition was fatal. This case highlights the importance of monitoring dogs closely for severe diarrhea after antibiotic treatment and considering further testing if symptoms worsen.

People also search for: dog diarrhea after antibiotics · Poodle colitis symptoms · antibiotic side effects in dogs

Abstract

A Poodle referred for renal disease developed severe colonic disease characterized by total mucosal collapse and necrosis. The onset of colonic disease was temporally related to administration of antibiotics. On 3 occasions, bacterial culture of fecal samples yielded only Streptococcus pyogenes, Pseudomonas aeruginosa, and Candida albicans, suggesting that the colonic bacterial flora was severely disrupted. Findings, although not conclusive, were suggestive of antibiotic-associated colitis that ultimately proved fatal. Colonoscopy should be considered for dogs with unduly severe large-bowel diarrhea associated with antibiotic treatment and can be done with minimal restraint and bowel preparation, if necessary. Nonselective bacterial culture of fecal samples should be considered for dogs with unduly severe large-bowel diarrhea associated with antibiotic treatment.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/9861973/