Peer-reviewed veterinary case report
Dog with spinal cord tumor and possible spread inside spine
By Terrell, S P et al.·Published in Veterinary pathology·2000·Department of Pathobiology, United States·View original on PubMed →
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Original publication title: Possible intraspinal metastasis of a canine spinal cord nephroblastoma.
- Species:
- dog
Plain-English summary
A 2-year-old Basset Hound was brought to the vet because it was having trouble walking and showed signs of weakness in its back legs. Sadly, during a post-mortem examination, doctors found tumors in the dog's spinal cord that were causing swelling and damage. These tumors were identified as nephroblastomas, which are a type of kidney tumor that can spread to the spine. This case is notable because it appears to be the first report of this type of tumor spreading within a dog's spinal cord. Unfortunately, the dog did not survive, highlighting the seriousness of this condition.
People also search for: Basset Hound back leg weakness · dog spinal cord tumor treatment · canine nephroblastoma symptoms
Abstract
A 2-year-old Basset Hound was admitted to the University of Florida Veterinary Medical Teaching Hospital with progressive spastic paraparesis. At necropsy, intradural extramedullary tumors produced areas of spinal cord swelling and softening in spinal cord segments T11-T12 and L4-L6. Histologic examination of the masses revealed sheets of polygonal blastemal cells, epithelial cells forming tubules and rosettes, and embryonal glomeruloid-like structures in the thoracic mass. Cells in the lumbar mass were less differentiated, forming rare tubules and no glomeruloid-like structures. The occurrence of two tumors in the spinal cord along with the less differentiated appearance of the lumbar tumor raises the possibility that the lumbar mass arose as a result of intraspinal metastasis. To our knowledge, this is the first report of multifocal or metastatic canine spinal nephroblastoma. In addition, the vimentin and cytokeratin immunohistochemical staining characteristics of these spinal cord nephroblastomas are described.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/10643988/