Peer-reviewed veterinary case report
Post-irradiation dietary vitamin E does not affect the development of radiation-induced lung damage in rats.
- Journal:
- Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
- Year:
- 2004
- Authors:
- Wiegman, Erwin M et al.
- Affiliation:
- Department of Radiation Oncology · Netherlands
- Species:
- rodent
Abstract
The purpose of this study was to investigate whether application of post-irradiation vitamin E, an anti-oxidant, could prevent the development of radiation induced lung damage. Wistar rats were given vitamin E enriched or vitamin E deprived food starting from 4 weeks after 18Gy single dose irradiation of the right thorax. Neither breathing frequencies nor CT density measurements revealed differences between the groups. It is concluded that post-irradiation vitamin E does not influence radiation-induced fibrosis to the lung.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/15236876/