Peer-reviewed veterinary case report
Hypothyroidism common after radiotherapy for dog thyroid cancer
By Amores‐Fuster, I. et al.·Published in Veterinary and Comparative Oncology·2015·Small Animal Teaching Hospital University of Liverpool Neston Wirral UK, United Kingdom·View original on Crossref →
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Original publication title: Post‐radiotherapy hypothyroidism in dogs treated for thyroid carcinomas
- Species:
- dog
Plain-English summary
Ten dogs with thyroid cancer developed hypothyroidism (low thyroid hormone levels) after receiving radiation therapy to treat their tumors. This condition was observed in about half of the dogs within six months after treatment, regardless of the specific radiation protocol used. Symptoms of hypothyroidism can include lethargy, weight gain, and changes in coat quality. It's important for pet owners to monitor their dogs' thyroid function after radiation therapy, as this can be a common side effect. Treatment for hypothyroidism typically involves hormone replacement therapy, which can help manage the condition effectively.
People also search for: dog thyroid cancer treatment · hypothyroidism symptoms in dogs · radiation side effects in dogs
Abstract
AbstractHypothyroidism is a common adverse event after head and neck radiotherapy in human medicine, but uncommonly reported in canine patients. Records of 21 dogs with histologically or cytologically confirmed thyroid carcinoma receiving definitive or hypofractionated radiotherapy were reviewed. Nine cases received48 Gyin 12 fractions, 10 received36 Gyin 4 fractions and 2 received32 Gyin 4 fractions. Seventeen cases had radiotherapy in a post‐operative setting. Ten cases developed hypothyroidism (47.6%) after radiotherapy. The development of hypothyroidism was not associated with the radiotherapy protocol used. Median time to diagnosis of hypothyroidism was 6 months (range, 1–13 months). Hypothyroidism is a common side effect following radiotherapy for thyroid carcinomas. Monitoring of thyroid function following radiotherapy is recommended. No specific risk factors have been identified.
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Search related cases →Original publication on Crossref: https://doi.org/10.1111/vco.12162