Peer-reviewed veterinary case report
Cancer risk and survival in cats after kidney transplant
By Wormser, C et al.·Published in Veterinary and comparative oncology·2016·Department of Surgery, United States·View original on PubMed →
PetCaseFinder translated the abstract of this peer-reviewed paper into plain English so pet owners can read it. We do not publish original research — every detail traces back to the citation above. How we work →
Original publication title: Post-transplant malignant neoplasia associated with cyclosporine-based immunotherapy: prevalence, risk factors and survival in feline renal transplant recipients.
- Species:
- cat
Plain-English summary
A group of 111 cats who received kidney transplants were found to have a higher risk of developing cancer, particularly lymphoma, compared to a group of 142 cats that did not have transplants. About 22.5% of the transplant cats were diagnosed with cancer, and while their overall survival time was similar to the non-transplant cats, those who developed cancer after their transplant had a much shorter survival time of just 13 days after diagnosis. This suggests that while kidney transplants can be life-saving, they may also increase the risk of certain cancers in cats.
People also search for: cat kidney transplant cancer risk · lymphoma in cats after transplant · feline renal transplant survival rates
Abstract
The study objective was to compare the prevalence of malignant neoplasia in feline renal transplant recipients (n = 111) with a control population of cats that did not receive transplantation (n = 142); and to determine whether the development of post-transplant malignant neoplasia (PTMN) affects long-term survival. Twenty-five (22.5%) renal transplant recipients were diagnosed with PTMN, and of those 14 (56%) were diagnosed with lymphoma. The overall survival time in cats that developed PTMN following renal transplantation (median 646 days, IQR 433-1620 days) was not significantly different from the survival time in cats that did not develop PTMN (median 728 days, IQR 201-1942 days), although median survival after diagnosis of PTMN was only 13 days. Six control cats (4.2%) were diagnosed with malignant neoplasia. Compared to the control population, transplant cats had a 6.6 times higher odds of developing malignant neoplasia and a 6.7 times higher odds of developing lymphoma.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/25303015/