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Peer-reviewed veterinary case report

Antibiotics don't lower eye surgery infection risk in dogs

By Piroth AC & Busse C.·2026·Department of Small Animal Medicine and Surgery, Germany·View original on Europe PMC

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Original publication title: Postoperative Antibiotics Do Not Prevent Surgical Site Infections After Routine Ophthalmic Soft Tissue Surgeries in Dogs-A Retrospective Study.

Species:
dog

Plain-English summary

A group of dogs that underwent eye surgeries, like eyelid repairs and enucleations (removal of the eye), were studied to see if giving antibiotics after surgery would prevent infections. The results showed that there was no difference in infection rates between dogs that received antibiotics and those that did not. Some factors, like being a brachycephalic breed (short-nosed) or having a higher body weight, were linked to a higher risk of infection. Overall, the study suggests that antibiotics may not be effective in preventing surgical site infections after these types of surgeries, indicating a need for better surgical care practices.

People also search for: dog eye surgery infection · antibiotics after dog surgery · brachycephalic dog surgery risks

Abstract

<h4>Purpose</h4>To compare the incidence of surgical site infections (SSI) following routine ophthalmic soft tissue surgeries in dogs receiving (AB) and not receiving (noAB) postoperative antibiotics.<h4>Methods</h4>Clinical records of dogs that underwent enucleations, wedge resections, medial canthoplasties, and simple and complicated eyelid surgeries with at least 3 months follow-up were retrospectively reviewed. SSI were recorded when increased mucoid or purulent discharge was present postoperatively or wound dehiscence occurred. SSI were graded based on Clavien-Dindo's classification according to the therapeutic intervention required.<h4>Results</h4>A total of 231 dogs (AB = 108; noAB = 123) met the inclusion criteria for enucleations, 135 for wedge resections (AB = 62; noAB = 73), 31 for medial canthoplasties (AB = 15; noAB = 16), and 30 and 22 for simple (AB = 13; noAB = 17) and complicated (AB = 7; noAB = 15) eyelid surgeries, respectively. There was no significant difference in SSI rates between patients receiving topical or systemic postoperative antibiotics and those not receiving antibiotics. Variables associated with an increased risk of SSI included a brachycephalic phenotype in eyelid wedge resections and high body weight in simple and complicated eyelid surgeries. The SSI were classified as grade 1 in 6/32 (18.8%) patients and grade 2 in 20/32 (62.5%) patients. 4/32 (12.5%) patients with SSIs were classified as grade 3b and required surgical intervention.<h4>Conclusion</h4>Postoperative systemic and topical antibiotics did not reduce SSI. The high incidence of SSI in medial canthoplasties and eyelid surgeries independent of postoperative antibiotic use highlights the need to reconsider pre-, peri- and postoperative protocols, including suture material selection and the implementation of wound cleaning routines.

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Original publication on Europe PMC: https://europepmc.org/article/MED/41932859