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Peer-reviewed veterinary case report

Cat's hyperparathyroidism returned after parathyroid surgery

By Ting, Tsz Fung & Pennington, Catrina·Published in Veterinary Record Case Reports·2025·Anderson Moores Veterinary Specialists Winchester UK, United Kingdom·View original on Crossref

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Original publication title: Postoperative recurrence of feline primary hyperparathyroidism (parathyromatosis)

Species:
cat
Drinking & peeingCats

Plain-English summary

A 14-year-old domestic shorthair cat was brought in for excessive thirst and urination, constipation, and high calcium levels, which led to a diagnosis of a parathyroid tumor. After surgery to remove the tumor, the cat's calcium levels returned to normal. However, two years later, the cat developed high calcium levels again, and after some tests, a new nodule was found and surgically removed. The biopsy confirmed it was a recurrence of the parathyroid tumor, and calcium levels normalized again after surgery. Unfortunately, the cat later developed kidney disease and was euthanized due to poor treatment response.

People also search for: cat high calcium levels · feline parathyroid tumor treatment · cat kidney disease symptoms

Abstract

AbstractThis report describes a case of suspected feline parathyromatosis, a rare condition defined as the development of new hyperfunctional parathyroid tissue in the neck, typically resulting from seeding during previous parathyroid surgery. A 14‐year‐old domestic shorthair cat was diagnosed with a left parathyroid adenoma after presenting with polyuria, polydipsia, constipation and hypercalcaemia. Thyro‐parathyroidectomy was performed, and ionised calcium levels normalised. Two years later, the cat developed recurrent hypercalcaemia with elevated parathyroid hormone. Physical examination was unremarkable, with no palpable mass on the neck. Ultrasonography of the abdomen and cervical region, along with thoracic radiography, yielded insignificant findings, and the cat was managed medically. Three months later, a palpable nodule was identified in the left subcutaneous cervical region and surgically excised. Histopathology confirmed the recurrence of parathyroid adenoma. Postoperatively, the ionised calcium levels normalised. The cat later developed acute‐on‐chronic kidney disease and was euthanased due to poor response to treatment.

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Original publication on Crossref: https://doi.org/10.1002/vrc2.70112