Peer-reviewed veterinary case report
Hormone changes after meals in lean and obese cats
By Martin, Lucile J M et al.·Published in The British journal of nutrition·2010·Unité, France·View original on PubMed →
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Original publication title: Postprandial response of plasma insulin, amylin and acylated ghrelin to various test meals in lean and obese cats.
- Species:
- cat
Plain-English summary
A study looked at how different types of food affect hormone levels in lean and obese cats. Five lean cats and five obese cats were fed high-protein, high-fat, and high-carbohydrate meals to see how their bodies responded. While the amount of food eaten was similar, obese cats consumed more calories overall. After eating, obese cats had higher levels of glucose and certain hormones compared to lean cats, especially after the high-protein meal. This suggests that the type of food can influence how cats process food and manage their weight, but more research is needed to fully understand these effects.
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Abstract
The propensity of diets of different composition to promote obesity is a current topic in feline medicine. The effects of three meals with different protein:fat ratios on hormones (insulin, acylated ghrelin and amylin) involved in the control of food intake and glucose metabolism were compared. Five lean (two females and three males, 28.6 (sd 3.4) % body fat mass (BFM), mean body weight (BW) 4590 g) and five obese (two females and three males, 37.1 (sd 4.1) % BFM, mean BW 4670 g) adult cats were studied. Only BFM differed significantly between obese and lean cats. The cats were fed a high-protein (HP), a high-fat and a high-carbohydrate diet in a randomised cross-over design. Food intake did not differ between cats fed on the different diets, but obese cats consumed significantly more energy, expressed as per kg fat-free mass, than lean cats. After a 6-week adaptation period, a test meal was given and blood samples were collected before and 0, 30, 60 and 100 min after the meal. Baseline concentrations of glucose, amylin and acylated ghrelin were higher in obese cats than in lean cats, and obese cats showed the highest postprandial responses of glucose and amylin. The HP diet led to higher postprandial amylin concentrations than the other diets, indicating a possible effect of amino acids on beta-cell secretion. Postprandial ghrelin concentrations were unaffected by diet composition. The relationship between insulin, amylin and ghrelin secretion and their relevant roles in food intake and glucose metabolism in cats require further study.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/20100379/