Peer-reviewed veterinary case report
Painful skin lumps and fever in dogs linked to potassium bromide
By Boynosky, N A & Stokking, L B·Published in The Journal of small animal practice·2014·Department of Dermatology, United States·View original on PubMed →
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Original publication title: Potassium bromide-associated panniculitis.
- Species:
- dog
Plain-English summary
Two dogs developed painful lumps under their skin after being treated with potassium bromide for epilepsy for over a year. The lumps, known as panniculitis, appeared on their bodies and were accompanied by tiredness and fever. After stopping the potassium bromide, the lumps and other symptoms went away and did not come back. This suggests that the medication may have caused the skin issue in these dogs.
People also search for: dog lumps under skin after medication · potassium bromide side effects in dogs · dog lethargy and fever treatment
Abstract
Two cases of panniculitis associated with administration of potassium bromide in dogs are reported. Both dogs were treated with potassium bromide for idiopathic epilepsy for over 1 year. Dose increases in both cases were associated with panniculitis, characterised by painful subcutaneous nodules in a generalised distribution over the trunk. Nodule eruption waxed and waned in one dog and was persistent in the other. In both cases, panniculitis was accompanied by lethargy and pyrexia. Panniculitis, lethargy and pyrexia resolved and failed to recur after discontinuation of potassium bromide. No other cause of panniculitis could be determined for either dog. Panniculitis has been reported after administration of potassium bromide in humans and may be a form of drug-induced erythema nodosum. To the authors' knowledge, these are the first reports of potassium bromide-associated panniculitis in dogs.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/24032452/