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Peer-reviewed veterinary case report

Pre-clinical Murine Models of Bone Sarcomas.

Journal:
Methods in molecular biology (Clifton, N.J.)
Year:
2025
Authors:
Muñoz-Garcia, Javier et al.
Affiliation:
Nantes Universit&#xe9 · France
Species:
rodent

Abstract

The present chapter gives a brief overview of the main murine models available for bone sarcoma studies, including genetically engineered mice. Particular attention will be paid to the different procedures to induce bone sarcoma from inoculation of tumor cells or implantation of tumor fragments. The technical aspects of anesthesia and surgical procedures, together with postoperative follow-up will be described and discussed in detail.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/40448772/