Peer-reviewed veterinary case report
Precision and accuracy of the Mindray BC-5000Vet hematology analyzer for canine and feline blood.
- Journal:
- Veterinary clinical pathology
- Year:
- 2020
- Authors:
- Thongsahuan, Sorawat et al.
- Affiliation:
- Faculty of Veterinary Science
Plain-English summary
The Mindray BC-5000Vet is a machine that helps veterinarians analyze blood samples from dogs and cats. Researchers tested its accuracy by comparing its results with traditional methods using blood from both healthy and sick pets. They found that the machine provided very reliable results for measuring red blood cells and white blood cells, with strong agreement between the machine and manual tests. Overall, the Mindray BC-5000Vet is a good tool for routine blood analysis in dogs and cats, even when there are blood-related health issues.
Abstract
BACKGROUND: The Mindray BC-5000Vet hematology analyzer is a flow cytometry-based automated hematology analyzer that generates a complete blood count with a five-part white blood cell (WBC) differential count. OBJECTIVES: We aimed to validate reliability results of the Mindray BC-5000Vet for use in dog and cat blood. METHODS: Imprecision was performed using the manufacturer's quality control material at low, normal, and high levels. Blood sample results of healthy and ill dogs and cats were studied for comparability between manual methods and the Mindray BC-5000Vet analyzer. Forty dogs and 40 cats were included in the study. RESULTS: Precision for red blood cell (RBC) parameters was excellent, with a coefficient of variation within-run (%CV) and between-run (%CV) of <2%. WBC count and differential count showed %CVand %CV<8%; however, %CVand %CVof low-level control material gave >9% eosinophils. The correlation between the BC-5000 Vet and manual methods in normal and abnormal canine and feline blood samples showed excellent correlations for the RBC counts, hemoglobin concentrations, hematocrits, and WBC counts (r > .93). The differential WBC analysis of canine blood showed good correlation (r = .80-.92). Feline blood samples showed excellent correlations for neutrophils and lymphocytes, with a good correlation for monocytes and eosinophils. CONCLUSIONS: The Mindray BC-5000Vet hematology analyzer proved a suitable instrument for routine analysis in dogs and cats with various hematologic abnormalities.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/32524640/