Peer-reviewed veterinary case report
How long eye drops stay on healthy dogs' eyes
By Bedos, L et al.·Published in Veterinary ophthalmology·2023·Department of Veterinary Clinical Sciences, United States·View original on PubMed →
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Original publication title: Precorneal retention time of ocular lubricants measured with fluorophotometry in healthy dogs.
- Species:
- dog
Plain-English summary
A group of six healthy Beagle dogs had their eyes treated with five different eye lubricants to see how long each one stayed on the eye's surface. The results showed that the Artificial Tears Ointment lasted the longest, staying effective for about 40 minutes, while the other lubricants had shorter retention times, with the Artificial Tears Solution lasting only about 10 minutes. This information can help veterinarians choose the best eye lubricant for dogs, ensuring that pets receive the most effective treatment for their eye care needs.
People also search for: dog eye lubricant effectiveness · Beagle eye care · how long do eye drops last for dogs
Abstract
OBJECTIVE: Determine the precorneal retention time of five different ocular lubricants commonly used in dogs. ANIMALS STUDIED: Six healthy Beagle dogs (n = 12 eyes). PROCEDURES: Five ocular lubricants were studied: Artificial Tears Solution® (1.4% polyvinyl alcohol), I-Drop® Vet Plus (0.25% hyaluronate), Optixcare® Eye Lube Plus (0.25% hyaluronate), Systane® Ultra (0.4% polyethylene glycol 400 and 0.3% propylene glycol), and Artificial Tears Ointment® (mineral oil/white petrolatum). Each lubricant was mixed with 10% sodium fluorescein to achieve 1% fluorescein formulations. Following topical administration of 35 mg in each eye, tear fluid was collected with capillary tubes at selected times (0, 1, 5, 10, 20, 30, 40, 50, 60, 90, 120, 180 min) and fluorescein concentrations were measured with a computerized scanning ocular fluorophotometer. RESULTS: Tear fluorescence was significantly greater with Artificial Tears Ointment® compared with other lubricant formulations from 1 to 20 min post-administration. Median (range) precorneal retention times were significantly different among the 5 lubricants, ranging from 40 minutes (20-90 min) for Artificial Tears Ointment®, 35 min (20-90 min) for Systane® Ultra, 30 min (10-60 min) for I-Drop® Vet Plus, 25 min (10-60 min) for Optixcare® Eye Lube Plus, and 10 min (10-20 min) for Artificial Tears Solution®. Precorneal retention time was significantly lower for Artificial Tears Solution® compared with the other 4 formulations. CONCLUSIONS: This study established normative data for the retention time of common lubricants on the ocular surface of dogs, which may be used to guide clinicians with their choice of lubricant and frequency of administration.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/36749146/