Peer-reviewed veterinary case report
Left atrial volume predicts pulmonary hypertension in dogs
By Woo, In-Sun & Kim, Jung-Hyun·Published in Frontiers in veterinary science·2024·Department of Veterinary Internal Medicine, South Korea·View original on PubMed →
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Original publication title: Predictive value of left atrial volumes assessed using real-time three-dimensional echocardiography for pulmonary hypertension in dogs with myxomatous mitral valve disease.
- Species:
- dog
Plain-English summary
A 7-year-old Cavalier King Charles Spaniel with myxomatous mitral valve disease (a heart condition) was evaluated for breathing problems. Researchers looked at heart images from 49 dogs like him to see if measuring the size of the left atrium (a heart chamber) could help predict pulmonary hypertension (high blood pressure in the lungs). They found that using a special 3D ultrasound technique provided the best results, showing that a larger left atrial volume was strongly linked to pulmonary hypertension. This information could help vets identify and manage heart issues in dogs more effectively.
People also search for: dog breathing problems · Cavalier King Charles Spaniel heart disease · pulmonary hypertension in dogs treatment
Abstract
INTRODUCTION: Left atrial volume (LAV) obtained using real-time three-dimensional echocardiography (RT3DE) is an independent predictor of post-capillary pulmonary hypertension (PH) in humans; however, no studies have investigated LAV obtained using RT3DE as a predictor of post-capillary PH in dogs with myxomatous mitral valve disease (MMVD). Therefore, we aimed to evaluate the clinical applicability of LAV obtained using RT3DE compared to that obtained using two-dimensional echocardiography (2DE) in dogs with MMVD, with or without PH. METHODS: Medical records and echocardiographic images of 237 privately owned dogs with naturally occurring MMVD with or without PH were retrospectively reviewed. A total of 49 privately owned dogs with naturally occurring MMVD, with or without PH, were finally included (35 MMVD without PH, 14 MMVD with PH). The LAV and left ventricular volumes were obtained using 2DE and RT3DE. Echocardiographic parameters were analyzed to identify independent predictors of post-capillary PH. RESULTS: We found that the left atrial and left ventricular volumes obtained using 2DE and RT3DE indexed to body weight and several 2DE-derived variables were univariately associated with post-capillary PH. Furthermore, multivariable logistic regression analysis revealed that the RT3DE minimum LAV indexed to body weight (LAVi min) was the only significant independent predictor of post-capillary PH (odds ratio, 12.86; 95% confidence interval [CI], 2.40-68.99; = 0.003), with the highest area under the curve value of 0.86 (95% CI, 0.75-0.96; < 0.001). DISCUSSION: In conclusion, LAV indexed to body weight obtained using 2DE and RT3DE, can be a useful predictor of post-capillary PH in dogs with MMVD. In particular, the RT3DE LAVi min was observed to be the strongest predictor of post-capillary PH.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/39220767/