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Peer-reviewed veterinary case report

Diabetes risk in cats after prednisolone treatment

By Sivert Nerhagen et al.·Published in Journal of feline medicine and surgery·2020·View original on Semantic Scholar

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Original publication title: Prednisolone-induced diabetes mellitus in the cat: a historical cohort

Species:
cat

Plain-English summary

A group of cats receiving a high dose of prednisolone, a common medication, were monitored for signs of diabetes. Out of 143 cats treated, 14 developed diabetes within three months of starting the medication, which is about 10% of the group. This means that if your cat is on prednisolone for more than three weeks, especially at higher doses, it's important to keep an eye on their blood sugar levels and watch for symptoms of diabetes. Regular check-ups with your veterinarian can help catch any issues early.

People also search for: cat diabetes symptoms · prednisolone side effects in cats · how to monitor cat blood sugar

Abstract

Objectives Prednisolone is a commonly used drug in cats and potential adverse effects include hyperglycaemia and diabetes mellitus. The aims of this study were to evaluate the frequency and investigate potential predisposing risk factors for the development of prednisolone-induced diabetes mellitus (PIDM) in cats. Methods The electronic records of a tertiary referral centre were searched for cats receiving prednisolone at a starting dose of ⩾1.9 mg/kg/day, for >3 weeks and with follow-up data available for >3 months between January 2007 and July 2019. One hundred and forty-three cats were included in the study. Results Of the 143 cats, 14 cats (9.7%) were diagnosed with PIDM. Twelve out of 14 cats (85.7%) developed diabetes within 3 months of the initiation of therapy. Conclusions and relevance Cats requiring high-dose prednisolone therapy should be closely monitored over the first 3 months of therapy for the development of PIDM.

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Original publication on Semantic Scholar: https://www.semanticscholar.org/paper/32716236