Peer-reviewed veterinary case report
Preputial diverticulum dilation in a Goettingen minipig.
- Journal:
- Laboratory animals
- Year:
- 2018
- Authors:
- Denk, Nora et al.
- Affiliation:
- Pharma Research and Early Development (pRED)
Abstract
Preputial dilation is an infrequently reported condition in pigs. The pathophysiology and etiology is unclear. Causes for diverticulum dilation are proposed to be chronic preputial diverticulitis with subsequent fibrosis of the preputial cavity, phimosis of the preputial orifice or the preputial diverticulum, but the large majority of cases are reportedly idiopathic in nature. Surgical interventions include ablative procedures, but many cases are not treated because of an assumed lack of clinical relevance in pigs not used for breeding. We report a case of progressive preputial dilation that recurred after surgical intervention. Histopathological examination revealed no primary inflammatory condition, contrary to literature suggesting a role for inflammatory mediators in pathogenesis. Phimosis of the preputial orifice was noted post mortem and might be a contributing factor. These findings partially contradict the current assumptions in regards to pathophysiology and treatment choices in the literature and warrant further investigation into alternative therapeutic interventions for this condition.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/28992802/