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Peer-reviewed veterinary case report

Presence of the exoU gene of Pseudomonas aeruginosa is correlated with cytotoxicity in MDCK cells but not with colonization in BALB/c mice.

Journal:
Journal of clinical microbiology
Year:
2006
Authors:
Lin, Hsi-Hsun et al.
Affiliation:
Department of Infectious Disease

Abstract

A total of 141 independent strains of Pseudomonas aeruginosa with different heterogeneities in the exo gene (exoS, exoT, exoU, and exoY) background were examined for their pathogenic roles. Results indicated that the exoU gene is the major contributor to cytotoxicity in Madin-Darby canine kidney cells but is not related to bacterial colonization in mice.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/17050810/