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Peer-reviewed veterinary case report

Border collie puppies with fever and joint swelling

By Mason, S L et al.·Published in The Journal of small animal practice·2014·School of Veterinary Science, United Kingdom·View original on PubMed

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Original publication title: Presentation and management of trapped neutrophil syndrome (TNS) in UK Border collies.

Species:
dog
Dog limpingMovement & jointsDogs

Plain-English summary

Three Border collie puppies in the UK were brought to the vet because they had fevers and were limping due to swollen joints. Tests showed they had low levels of a type of white blood cell (neutropenia), and X-rays indicated bone issues. They were diagnosed with trapped neutrophil syndrome, a condition that affects their immune response. After treatment with steroids (prednisolone) and antibiotics, all three puppies improved and grew up healthy.

People also search for: Border collie puppy fever · trapped neutrophil syndrome treatment · dog limping with joint swelling

Abstract

Three UK bred Border collie puppies were presented for investigation of pyrexia and severe lameness with associated joint swelling. Investigations revealed neutropenia, radiographic findings suggesting metaphyseal osteopathy, and polyarthritis and all dogs were subsequently confirmed with trapped neutrophil syndrome. Clinical improvement was seen after treatment with prednisolone and antibiotics and the dogs all survived to adulthood with a good short- to medium-term outcome. Trapped neutrophil syndrome is an important differential diagnosis for young Border collie dogs in the UK presenting with pyrexia, neutropenia and musculoskeletal signs.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/24032537/