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Peer-reviewed veterinary case report

Risk factors for severe urine loss after blocked urethra in male cats

By Muller, Kelly M et al.·Published in Frontiers in veterinary science·2022·School of Veterinary Medicine, United States·View original on PubMed

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Original publication title: Presentation Variables Associated With the Development of Severe Post-obstructive Diuresis in Male Cats Following Relief of Urethral Obstruction.

Species:
cat

Plain-English summary

A group of male cats with urethral obstruction were treated at a veterinary hospital, and many experienced a serious complication called post-obstructive diuresis (POD) after their blockage was relieved. About 68% of these cats had some level of POD, with 35% suffering from severe cases, which can be life-threatening. Factors like lower body weight and certain blood test results were linked to a higher risk of developing severe POD. Cats with severe POD needed to stay in the hospital for about a day longer than those without this complication.

People also search for: cat urethral obstruction treatment · male cat urinary blockage symptoms · post-obstructive diuresis in cats

Abstract

BACKGROUND: Diuresis following relief of urethral obstruction is a potentially life-threatening complication of feline urethral obstruction. Evidence regarding the incidence of post-obstructive diuresis (POD) in cats is scarce. Establishing historical, physical examination, and initial clinicopathologic variables associated with risk for developing POD may better enable clinicians to direct treatment for this common feline emergency and to educate clients regarding financial expectations. OBJECTIVES: To report the incidence of POD in a large group of cats with urethral obstruction and determine whether select presenting physical examination or initial clinicopathologic variables may predict the onset or severity of POD. METHODS: The records of 260 cats that were admitted to the University of California, Davis, Veterinary Medical Teaching Hospital for urethral obstruction were reviewed. Urine output after urethral catherization was categorized into no POD (urine output &#x2264; 2 mL/kg/h), mild-moderate POD (urine output > 2 but <5 mL/kg/h) and severe POD (urine output &#x2265; 5 mL/kg/h). Select presentation physical examination, venous acid-base, electrolyte, serum biochemistry, and urinalysis results were compared among the groups. RESULTS: 67.7% of cats experienced POD, and in 35% of cats it was categorized as severe. Evaluated historical and physical examination variables correlated with development of POD were lower body weight and, for severe POD, hypovolemia. Clinicopathologic variables associated with development of POD included acidemia, azotemia, hyperphosphatemia, hyperkalemia, hyponatremia, hypochloremia, hypocalcemia, hypermagnesemia, and hypoalbuminemia. Cats with severe POD were hospitalized a median of 1 day longer than those without POD. CONCLUSIONS: Results of the present study indicate that there are presentation variables associated with onset and severity of POD following relief of feline urethral obstruction.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/35450137/