Peer-reviewed veterinary case report
Presumed moxidectin toxicosis in three foals.
- Journal:
- Journal of the American Veterinary Medical Association
- Year:
- 1999
- Authors:
- Johnson, P J et al.
- Affiliation:
- Department of Veterinary Medicine and Surgery · United States
- Species:
- horse
Plain-English summary
This study looked at three young foals, all under four months old, that were given a medication called moxidectin, which is a type of dewormer. After receiving the medication, two of the foals fell into a coma but were able to recover with supportive care. Unfortunately, one foal lost consciousness and did not survive. The findings suggest that there is a risk of overdose with moxidectin, especially since horse owners may not fully understand how to use the syringe properly. Overall, the results indicate that moxidectin should not be given to foals younger than four months due to the high risk of serious side effects.
Abstract
Outcome and complications associated with administration of moxidectin gel to 3 foals < 4 months old are described. Two foals became comatose but survived following supportive treatment. One foal died following loss of consciousness associated with moxidectin administration. Risk of moxidectin overdose exists, because horse owners often fail to read or comprehend the package insert instructions pertaining to use of the syringe-locking mechanism. In addition, moxidectin should not be administered to foals < 4 months old, because it is likely that treated foals will become comatose.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/10088018/