Peer-reviewed veterinary case report
Addison's disease signs and rates in Great Pyrenees dogs
By Decôme, Magali & Blais, Marie-Claude·Published in The Canadian veterinary journal = La revue veterinaire canadienne·2017·Department of Clinical Sciences·View original on PubMed →
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Original publication title: Prevalence and clinical features of hypoadrenocorticism in Great Pyrenees dogs in a referred population: 11 cases.
- Species:
- dog
Plain-English summary
A group of Great Pyrenees dogs was found to have a higher rate of Addison's disease (hypoadrenocorticism) compared to other breeds, with symptoms like anemia, low blood pressure, and weight loss. Out of 100 dogs diagnosed with this condition, nearly 10% were Great Pyrenees. While the symptoms can be vague and similar to other health issues, these dogs often showed specific signs like low red blood cell counts and increased white blood cells. Treatment typically involves hormone replacement therapy, which can help manage the symptoms effectively.
People also search for: Great Pyrenees Addison's disease symptoms · dog low blood pressure treatment · anemia in dogs causes
Abstract
Naturally occurring hypoadrenocorticism (Addison's disease) is uncommon, with an estimated prevalence in the canine population between 0.06% and 0.28%. This retrospective study evaluated the prevalence and clinical features of hypoadrenocorticism in Great Pyrenees (GP) dogs presented to the Centre Hospitalier Universitaire Vétérinaire of the University of Montreal between March 2005 and October 2014. During this period, 100 dogs were diagnosed with hypoadrenocorticism, representing 0.38% [95% confidence interval (CI): 0.26% to 0.5%] of the canine population studied. The highest prevalence was observed in GP (9.73%, 95% CI: 9.12% to 10.35%,< 0.0001), followed by West Highland white terriers (4.66%, 95% CI: 4.24% to 5.09%,< 0.0001), Great Danes (1.87%, 95% CI: 1.6% to 2.14%,< 0.0001), standard poodles (1.76%, 95% CI: 1.5% to 2.02%,= 0.0001), Saint Bernards (1.72%, 95% CI: 1.47% to 1.98%,= 0.018), and Jack Russell terriers (1.48%, 95% CI: 1.24% to 1.72%,= 0.003). Although most clinical features were nonspecific, Great Pyrenees dogs were more frequently presented with anemia, azotemia, and eosinophilia, or with hypotension and cachexia compared with dogs of other breeds.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/28966360/