Peer-reviewed veterinary case report
Cholecystitis in dogs with gallbladder mucocele and survival outcomes
By Rogers, Erin et al.·Published in Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001)·2020·Department of Veterinary Medicine and Surgery·View original on PubMed →
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Original publication title: Prevalence and impact of cholecystitis on outcome in dogs with gallbladder mucocele.
- Species:
- dog
Plain-English summary
A study found that nearly 29% of dogs with gallbladder mucocele, a serious condition affecting the gallbladder, also had cholecystitis (inflammation of the gallbladder). The most common types of cholecystitis observed were acute on chronic and those with tissue death. Despite the presence of cholecystitis in these dogs, it did not seem to affect their chances of survival. Out of the 219 dogs studied, 38 either died or were euthanized during their hospital stay, but the presence of cholecystitis did not correlate with these outcomes.
People also search for: dog gallbladder mucocele treatment · symptoms of cholecystitis in dogs · dog gallbladder surgery recovery
Abstract
BACKGROUND: Gallbladder mucocele is a potentially life-threatening extrahepatic biliary disease in dogs. The primary aims of this study were to evaluate the prevalence of cholecystitis in dogs with gross and histopathologically confirmed gallbladder mucocele and to investigate if there is an association between cholecystitis, including its subtypes (eg, acute, acute on chronic, with necrosis, chronic), and survival. Our secondary objective was to evaluate if there is an association between cholecystitis and intraoperative bacteriological culture positivity. KEY FINDINGS: Two hundred nineteen dogs with gallbladder mucocele were included in this multi-institutional retrospective study, of which 63 (28.8%) dogs had histopathological evidence of cholecystitis. The most common forms of cholecystitis were acute on chronic (n = 22/63, 34.9%) and with necrosis (n = 20, 31.7%). Thirty-one (14.1%) dogs had growth of at least 1 bacterial isolate; however, 88.7% had antimicrobials administered within the 48 hours before surgery or intraoperatively. There was not an association between cholecystitis or its subtypes and survival. Furthermore, there was not an association between cholecystitis and intraoperative bacteriological culture positivity. A total of 38 (17.4%) dogs either died or were euthanized during hospitalization. SIGNIFICANCE: Cholecystitis is a common comorbidity in dogs with gallbladder mucocele but was not associated with decreased survival.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/31854510/