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Peer-reviewed veterinary case report

Neurological disorders in Cavalier King Charles Spaniels at referral

By Katie Brown et al.·Published in BSAVA Congress Proceedings 2019·2019·View original on Semantic Scholar

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Original publication title: Prevalence of neurological disorders in Cavalier King Charles Spaniels in neurology referral populations

Species:
dog

Plain-English summary

A 1-year-old Cavalier King Charles Spaniel was brought in with neck pain and a fever, showing signs of a condition called steroid-responsive meningitis-arteritis (SRMA), which is an immune system disorder affecting the brain's protective layers. During treatment, the dog also developed osteoma cutis, a rare skin condition where bone forms in the skin, likely linked to previous steroid use. The veterinarian treated the SRMA with prednisolone, a common steroid, and added cytarabine, which successfully helped manage the symptoms. The dog improved with treatment and showed a positive response to the medications.

People also search for: Cavalier King Charles Spaniel neck pain · SRMA treatment in dogs · osteoma cutis in dogs

Abstract

Osteoma cutis refers to heterotropic ossification within the skin. Whilst veterinary reports are few, a number of cases suggest an association of osteoma cutis in dogs with chronic glucocorticoid therapy. Steroid Responsive Meningitis Arteritis (SRMA) is an immune mediated inflammatory disorder of the leptomeninges and associated arteries. It is typically seen in young dogs between 6 and 18 months. Patients commonly present with cervical pain and pyrexia. Prednisolone monotherapy is the mainstay of treatment. We report a case of osteoma cutis in a dog with a concurrent relapse of SRMA. We also report the use of cytarabine as a successful treatment for the SRMA. METHODS

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Original publication on Semantic Scholar: https://www.semanticscholar.org/paper/5b590a45edcf169da4d77ffff46e6b85d86adf02