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Peer-reviewed veterinary case report

Thyroglobulin autoantibodies found in hypothyroid and healthy dogs

By Lee, J Y et al.·Published in Research in veterinary science·2004·Department of Veterinary Clinical Science, Japan·View original on PubMed

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Original publication title: Prevalence of thyroglobulin autoantibodies detected by enzyme-linked immunosorbent assay of canine serum in hypothyroid, obese and healthy dogs in Japan.

Species:
dog

Plain-English summary

A group of dogs in Japan was tested for a type of antibody related to thyroid problems. Out of 19 dogs with hypothyroidism, 10 had these antibodies, while only one dog each from the obese and healthy groups tested positive. Notably, a healthy dog that tested positive also showed signs of hypothyroidism, including low thyroid hormone levels. Golden Retrievers were particularly affected, with a high number of hypothyroid dogs in the study. This information can help veterinarians better understand and diagnose thyroid issues in dogs.

People also search for: dog thyroid problems symptoms · hypothyroidism in Golden Retrievers · dog thyroid test results

Abstract

Thyroglobulin autoantibodies (TgAA) were detected in sera of hypothyroid (n=19), obese (n=28) and clinically healthy dogs (n=52) using a commercially available immunoassay kit. TgAA-positive results occurred in 10 of 19 hypothyroid, 1 of 28 obese and 1 of 52 clinically healthy dogs. The clinically healthy TgAA-positive dog had additional evidence of hypothyroidism supported by low total T(4), low free T(4) and high canine TSH. Among the breeds, Golden Retriever had the highest frequency of hypothyroid (9/19) and TgAA-positive hypothyroid dogs (6/10). This study was the first survey about the prevalence of canine TgAA in Japan and could be a useful reference for clinicians.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/14672855/