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Peer-reviewed veterinary case report

Preventing Cardiogenic Thromboembolism in Cats: Literature Gaps, Rational Recommendations, and Future Therapies.

Journal:
The Veterinary clinics of North America. Small animal practice
Year:
2023
Authors:
Shaverdian, Meg & Li, Ronald H L
Affiliation:
Department of Surgical and Radiological Sciences · United States
Species:
cat

Abstract

Cardiogenic arterial thromboembolism (CATE) is a devastating complication in cats with cardiomyopathies with significant morbidity and mortality. Despite recent advances in the diagnosis and treatment of CATE, its recurrence and mortality remain high. This highlights the urgent need for a greater understanding of CATE pathophysiology so that novel diagnostic tests and therapeutics can be developed. This comprehensive review aims to summarize existing literature on pathophysiology, clinical diagnosis, and current recommendations on the prevention and treatment of CATE. It also identifies and describes knowledge gaps and research priorities in the roles of immunothrombosis and procoagulant platelets in the pathogenesis of CATE.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/37516545/