Peer-reviewed veterinary case report
How NexGard stops Babesia rossi tick infection in dogs
By Beugnet, Frederic et al.·Published in Parasite (Paris, France)·2019·Boehringer-Ingelheim, France·View original on PubMed →
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Original publication title: Prevention of the transmission of Babesia rossi by Haemaphysalis elliptica in dogs treated with Nexgard.
- Species:
- dog
Plain-English summary
A group of dogs was tested to see if a flea and tick treatment called NexGard could prevent infection from a specific tick-borne disease caused by Babesia rossi. The study found that dogs treated with NexGard had no infections, while untreated dogs had a 100% infection rate after being exposed to infected ticks. The results showed that NexGard effectively protected the dogs from this disease for at least 28 days. If you're worried about ticks and tick-borne diseases, this treatment could be a good option for your dog.
People also search for: dog tick prevention NexGard · Babesia rossi in dogs · how to protect dog from ticks
Abstract
This experimental study aimed to determine the efficacy of Afoxolaner (NexGard) to prevent Babesia rossi transmission by Haemaphysalis elliptica ticks on dogs. The study included three groups of seven dogs each. Groups 1 and 2 remained untreated, whereas group 3 dogs received NexGardon Day 0. All dogs were infested by 50 Haemaphysalis elliptica adult ticks: Group 1 on Day 2, Group 2 on Day 28 and Group 3 on Days 2 and 28. The ticks were originally nymphs having fed on B. rossi infected donor dogs. Their infection rate, assessed by PCR, was 12.8% at Day 2 and 6% at Day 28. On Days 0, 7, 14, 21, 28, 35, 42, 49 and 56, and in case of suspicion of babesiosis, blood samples were collected for blood smears, PCR and ELISA. The B. rossi infection rate in the untreated group 1 was 100% (6/6, as one dog was inadvertently treated on Day 15 and removed from statistical analysis). The infection rate was 57.1% (4/7) in group 2, and 0% (0/7) in the afoxolaner treated group 3 at all time-points until the end of the study on Day 56. After tick removal and count 144 h after each infestation, the control groups had an arithmetic mean of ticks of 23.8 (group 1) and 26.8 (group 2). No tick was recovered from any treated dogs. This study demonstrated that NexGardprotected dogs against infection by B. rossi for at least 28 days.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/31432778/