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Peer-reviewed veterinary case report

Topical treatment prevents ear mites in naturally exposed cats

By Beugnet, Frédéric et al.·Published in Parasite (Paris, France)·2014·Merial, France·View original on PubMed

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Original publication title: Preventive efficacy of a topical combination of fipronil--(S)-methoprene--eprinomectin--praziquantel against ear mite (Otodectes cynotis) infestation of cats through a natural infestation model.

Species:
cat
Skin & coatCats

Plain-English summary

A group of cats was tested for ear mites (Otodectes cynotis) to see if a topical treatment could prevent infestation. Six cats received a combination treatment, while six others did not. After a month, the untreated cats had a significant number of live mites, while only three treated cats had a few mites, showing the treatment was 96% effective. The untreated cats also showed signs of ear irritation, while the treated cats did not. This suggests that the topical treatment is very effective in preventing ear mite infestations in cats.

People also search for: cat ear mites treatment · how to prevent ear mites in cats · signs of ear mites in cats

Abstract

A study based on naturally infested cats was designed to evaluate the effectiveness of a single treatment with a topical formulation containing fipronil, (S)-methoprene, eprinomectin and praziquantel, for the prevention of Otodectes cynotis infestation in cats. Six treated cats and six untreated cats were housed with three chronically Otodectes cynotis-infested cats, respectively. The cats of each group were kept together in a 20-m(2) room for 1 month. Both clinical examination and ear mite counts were conducted on Day 28. All donor cats were confirmed to be chronically infested with Otodectes cynotis on Day -1 and Day 28. From untreated control cats, 129 live mites were recovered on Day 28 and all cats were found to be infested. In the treated group, three cats were found to be infested, with a total of five live mites recovered, the difference between the two groups being significant (p = 0.003). One treatment corresponded to 96% preventive efficacy at Day 28 based on ear mite counts. With regard to cerumen, the clinical score increased significantly for untreated cats between Day -1 and Day 28 (p = 0.00026) and not for treated cats (p = 0.30). The difference in cerumen abundance was significant between untreated and treated cats on Day 28 (p = 0.0035). Concerning the pruritic reflex in at least one ear, all cats were negative at inclusion. All six untreated cats became positive and showed a reflex on Day 28, whereas no treated cat showed ear pruritus (p = 0.00026).

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/25148648/