Peer-reviewed veterinary case report
Dog with liver chondrosarcoma and tumor recurrence after surgery
By Chikata, S et al.·Published in Veterinary pathology·2006·Department of Veterinary Pathology, Japan·View original on PubMed →
PetCaseFinder translated the abstract of this peer-reviewed paper into plain English so pet owners can read it. We do not publish original research — every detail traces back to the citation above. How we work →
Original publication title: Primary chondrosarcoma in the liver of a dog.
- Species:
- dog
Plain-English summary
A 6-year-old male Golden Retriever was diagnosed with a rare type of liver cancer called primary chondrosarcoma. After surgery to remove part of the liver, the cancer came back after six months, and unfortunately, the dog passed away ten months later due to the spread of the disease. This type of tumor is unusual because it starts in the liver rather than in the bones or cartilage, which is more common for chondrosarcomas. Sadly, this case highlights the aggressive nature of this cancer and the challenges in treating it effectively.
People also search for: dog liver cancer symptoms · Golden Retriever cancer treatment · chondrosarcoma in dogs
Abstract
Primary chondrosarcoma was found in the quadrate lobe of the liver of a 6-year-old, intact, male Golden Retriever. At 6 months after partial hepatectomy, recurrence in the liver occurred. The dog died of its systemic metastases 10 months thereafter. Histologically, the hepatic mass revealed neoplastic chondrocytes with abundant chondroid matrix, and there were few myxoid areas where the cellularity and pleomorphism of the neoplastic cells were more prominent. The neoplastic cells were positive for periodic acid-Schiff and were immunohistochemically positive for vimentin and S-100 protein; the matrix was deeply stained for alcian blue and was metachromatic for toluidine blue stain. This tumor might be derived from pluripotent mesenchymal cells in the connective tissue of the liver. To the best of our knowledge, in all mammalians, including humans, this is the first report of extraskeletal chondrosarcoma primarily arising in the liver.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/17099168/