Peer-reviewed veterinary case report
Respiratory disease from 7 weeks in a Staffordshire bull terrier
By De Scally, M et al.·Published in Journal of the South African Veterinary Association·2004·Bryanston Veterinary Hospital·View original on PubMed →
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Original publication title: Primary ciliary dyskinesia in a Staffordshire bull terrier.
- Species:
- dog
Plain-English summary
A 14-week-old Staffordshire bull terrier was brought in for breathing problems that started when he was just 7 weeks old. The puppy had pneumonia, which was confirmed through X-rays and tests of his airways. Further examination revealed that he had primary ciliary dyskinesia, a condition affecting the tiny hair-like structures in his lungs that help clear mucus and debris, leading to repeated respiratory infections. This case is notable as it is the first reported instance of this condition in a Staffordshire bull terrier and in South Africa. Treatment details were not specified, but managing respiratory infections and monitoring would be crucial for his care.
People also search for: Staffordshire bull terrier breathing problems · puppy pneumonia treatment · primary ciliary dyskinesia in dogs
Abstract
Primary ciliary dyskinesia (PCD) is a diverse group of inherited structural and functional abnormalities of the respiratory and other cilia, which results in recurrent respiratory tract infections. Primary ciliary dyskinesia was diagnosed in a 14-week old Staffordshire bull terrier that had a history of respiratory disease from 7 weeks of age. Pneumonia was diagnosed on thoracic radiographs and transtracheal aspirate. Transmission electron microscopy of the bronchi and trachea indicated the presence of both primary and secondary ciliary dyskinesia. The most prominent primary defects consisted of absent inner dyneim arms, absent radial spokes and absence of the central microtubules. These defects accounted for 62% of the total number of cross-sections screened. Non-specific ciliary abnormalities encountered most often were compound cilia, swollen cilia, addition/deletion of peripheral doublets and disorganised axonemes (26%). To the authors' knowledge, this is the first case of PCD described in the Staffordshire bull terrier and the first report of PCD in South Africa.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/15628808/