Peer-reviewed veterinary case report
Corneal tumors linked to pigmentary keratitis in four dogs
By Bernays, M E et al.·Published in Journal of the American Veterinary Medical Association·1999·Kessels Road Veterinary Hospital, Australia·View original on PubMed →
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Original publication title: Primary corneal papilloma and squamous cell carcinoma associated with pigmentary keratitis in four dogs.
- Species:
- dog
Plain-English summary
Four dogs, including three brachycephalic breeds with protruding eyes, were found to have growths on their corneas. These growths included one case of a benign papilloma and three cases of squamous cell carcinoma, which can be linked to long-term exposure to sunlight and other mechanical factors. The dogs had a history of pigmentary keratitis, a condition that can lead to changes in the cornea. Treatment options for these conditions should be discussed with a veterinarian, as early diagnosis and intervention can be crucial for the best outcome.
People also search for: dog corneal growth treatment · squamous cell carcinoma in dogs · pigmentary keratitis in dogs · dog eye problems · brachycephalic dog eye care
Abstract
Squamous cell carcinoma (SCC) and squamous papilloma are rarely reported as primary lesions of the cornea in dogs. One case of corneal papilloma and 3 cases of SCC, each arising as a primary central corneal neoplasm rather than spreading from adjacent limbal conjunctiva, were reviewed. The most common cause of SCC in animals is chronic exposure of lightly pigmented epithelium to UV light; however, all dogs in this study had a history of chronic pigmentary keratitis. Three of the 4 dogs were of brachycephalic breeds with naturally proptotic eyes and oversized palpebral fissures that may have exposed the cornea to greater excessive solar radiation. Alternatively, mechanical factors that caused chronic changes in the cornea may have been causative factors for induction of primary dysplastic or neoplastic changes. Primary corneal neoplasia should be considered in the differential diagnosis of corneal masses.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/9926011/