Peer-reviewed veterinary case report
Canine transmissible venereal tumor with Leishmania in skin nodules
By Albanese, Francesco et al.·Published in Veterinary dermatology·2002·Practitioner, Italy·View original on PubMed →
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Original publication title: Primary cutaneous extragenital canine transmissible venereal tumour with Leishmania-laden neoplastic cells: a further suggestion of histiocytic origin?
- Species:
- dog
Plain-English summary
A 5-year-old mixed-breed dog was brought in with three hairless lumps on its neck and back. The veterinarian diagnosed the dog with a transmissible venereal tumor (TVT), a type of tumor that can spread between dogs. During tests, they found that the tumor cells contained Leishmania parasites, which are usually associated with a disease that affects the skin and internal organs. The dog received treatment for the tumor, and the presence of the parasites suggested a unique connection to the tumor's origin.
People also search for: dog skin lumps · transmissible venereal tumor treatment · Leishmania in dogs
Abstract
The clinical signs and histopathological features of a primary extragenital canine transmissible venereal tumour (TVT) are described. Three subcutaneous round alopecic nodules were located on the anterior and caudal dorsal region and in the ventral area of the neck. Cytologically, tumour cells were intermediate in size with a moderate amount of cytoplasm, and the nuclei were immature with finely reticular chromatin. The cytoplasm was lightly to heavily basophilic and contained distinct small vacuoles at the periphery. On the basis of these characteristics, a diagnosis of TVT was made and confirmed by histological and ultrastructural investigations. Leishmania amastigotes were detected in the cytoplasm of macrophages and neoplastic cells of the tumoral mass. The presence of the parasite within neoplastic cells is consistent with a histiocytic origin of TVT.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/12358607/