Peer-reviewed veterinary case report
Malignant spindle-cell tumor in right atrium of a dog
By Wohlsein, P et al.·Published in Journal of comparative pathology·2005·Institut fü, Germany·View original on PubMed →
PetCaseFinder translated the abstract of this peer-reviewed paper into plain English so pet owners can read it. We do not publish original research — every detail traces back to the citation above. How we work →
Original publication title: Primary endocardial malignant spindle-cell sarcoma in the right atrium of a dog resembling a malignant peripheral nerve sheath tumour.
- Species:
- dog
Plain-English summary
A 7-year-old male hunting terrier was diagnosed with a rare and aggressive tumor in the right atrium of his heart. This tumor, which is a type of malignant spindle-cell sarcoma, was growing into the heart's wall and causing serious health issues. Unfortunately, due to the nature of this tumor, treatment options are limited, and the prognosis is often poor. If your dog shows signs of heart problems, such as coughing, difficulty breathing, or lethargy, it's important to consult your veterinarian for further evaluation.
People also search for: dog heart tumor symptoms · hunting terrier heart problems · malignant tumor treatment in dogs
Abstract
An unusual malignant spindle-cell sarcoma in the right atrium of a 7-year-old male hunting terrier is described. The neoplasm arose from the endocardium, protruded into the lumen of the right atrium, was covered with endothelium, and showed local invasive growth into the atrial wall. The tumour was composed of interlacing bundles of spindle cells, sometimes arranged in whorls resembling the Antoni type A pattern. The extracellular matrix showed abundant reticulin fibres. Immunohistochemistry revealed an intense labelling of tumour cells for vimentin, and a partial labelling for neuron-specific enolase, S100 protein, and Melan-A. The morphology of the tumour indicated a primary malignant peripheral nerve sheath tumour, resembling a neoplasm described in rats.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/15893992/