Peer-reviewed veterinary case report
Cat developed primary hyperparathyroidism after radioiodine therapy
By Ruane, E et al.·Published in The Journal of small animal practice·2025·Department of Veterinary Medicine, United Kingdom·View original on PubMed →
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Original publication title: Primary hyperparathyroidism in a domestic shorthair cat following Iradioiodine therapy.
- Species:
- cat
Plain-English summary
A 12-year-old male neutered domestic shorthair cat was brought in for a cervical mass after receiving radioiodine therapy for hyperthyroidism two years earlier. Tests showed that the mass was likely a tumor related to primary hyperparathyroidism, which can cause high calcium levels in the blood. The cat underwent surgery to remove the mass, and afterward, both the hyperparathyroidism and high calcium levels completely resolved. This case highlights a rare occurrence of primary hyperparathyroidism in cats following radioiodine treatment.
People also search for: cat cervical mass · hyperparathyroidism in cats · cat surgery for tumor · radioiodine therapy side effects in cats
Abstract
A 12-year-old male neutered domestic shorthaired cat presented for further assessment of a cervical mass, having undergone radioiodine therapy for treatment of hyperthyroidism 2 years prior to presentation. Initial cytological diagnosis of the mass was supportive of a carcinoma and laboratory results were consistent with primary hyperparathyroidism. Thoracic radiographs and magnetic resonance imaging were performed of the neck prior to surgical removal of the mass. Histopathology and immunohistochemical characteristics were supportive of a parathyroid tumour. Primary hyperparathyroidism and the associated hypercalcaemia fully resolved following surgery. In human medicine, there is awareness of an association between radioactive iodine therapy and development of primary hyperparathyroidism. Based on our literature search, this sequence of pathologies has not been reported in cats. This report documents primary hyperparathyroidism in a cat following radioiodine therapy.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/40169934/