Peer-reviewed veterinary case report
Heart murmur and infundibular stenosis in Golden Retriever puppies
By Arndt, Jason et al.·Published in Journal of the American Animal Hospital Association·2012·University of Pennsylvania School of Veterinary Medicine, United States·View original on PubMed →
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Original publication title: Primary infundibular stenosis and pedigree analysis in three Golden Retriever littermates.
- Species:
- dog
Plain-English summary
Three eight-week-old Golden Retriever puppies were found to have a heart murmur during a check-up and were diagnosed with primary infundibular stenosis, a heart condition that can lead to serious issues. Although all three puppies showed no symptoms at the time, two had additional congenital heart defects. The condition is believed to be inherited in an autosomal recessive pattern, meaning both parents likely carried the gene. It's important for Golden Retriever owners to be aware of this condition, as it can worsen over time.
People also search for: Golden Retriever heart murmur · primary infundibular stenosis in puppies · congenital heart defects in dogs
Abstract
Three eight-week-old Golden Retriever puppy littermates were evaluated because of left basilar systolic murmurs and were diagnosed with primary infundibular stenosis. Pedigree analysis in this line was also performed to identify a mode of inheritance. All dogs were asymptomatic at the time of diagnosis; two of the three had congenital lesions in addition to primary infundibular stenosis. Two additional affected dogs were identified in the line, and pedigree analysis suggested an autosomal recessive mode of inheritance. Another, unrelated golden retriever was also identified with isolated infundibular stenosis in the record database. Primary infundibular stenosis should be considered in the differential diagnoses for golden retriever dogs with a left basilar systolic murmur, and is often associated with complex congenital cardiac disease. Primary infundibular stenosis may worsen in severity with time, and in this line of dogs an autosomal recessive pattern of inheritance is likely.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/22186718/